Corona Virus: Hepatitis in children – Corona virus may be the cause

Immunology

Hepatitis in children: Corona may be the cause

hepatitis disease

hepatitis disease

Hepatitis viruses are dangerous. The video explains how and when the disease affects itself after infection.

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Is the accumulation of hepatitis in children related to corona? A new study supports this thesis. But she has been criticized.

Berlin. A new study from Israel claims to have found evidence of the unusual accumulation of Cases of hepatitis in childrenWhich has been receiving international attention for weeks, may be linked to Corona. Inflammation can be a long-term side effect of SARS-CoV-2 infection. German scientists consider the conclusions premature.

According to the European Center for Disease Prevention and Control (ECDC), as of June 9, more than 400 cases of acute hepatitis of unknown origin in children up to 16 years of age have been reported from the European region. The World Health Organization is talking about About 700 cases worldwide. The association with COVID-19 disease alone or in combination with another viral infection, primarily caused by adenoviruses, has been discussed for weeks.

In a small case study published in the “Journal of Pediatric Gastroenterology and Nutrition,” Israeli researchers now describe five cases of liver and bile duct damage in children, all of whom previously tested positive for Covid 19 infection. All had an asymptomatic or mild course.






Hepatitis in children: evidence of an overactive immune reaction and inflammation

One event in two healthy three- and five-month-old infants CirrhosisWhich quickly led to a liver transplant. The other three children, ages 8 to 13, had hepatitis B with stasis. According to the study, investigations into other infectious causes of liver damage have not been successful. However, there were many indications of a strong immune reaction and persistent inflammation.

Scientists talk about the “Long Covid-19 Liver Manifestation” in the title of their study. Additionally, they have formulated the hypothesis that damage to the liver or gallbladder can be rare Long-term side effects For CovidD-19 infection in children.


Of the total 273 cases of pediatric hepatitis in the European Union diagnosed with PCR test According to the ECDC, only 29 (10.6 percent) have tested positive for Sars-CoV-2. However, indications of prior infection using blood values ​​were only available for 47 cases, of which 30 (63.8) were positive. Of the 94 cases with information on the Covid 19 vaccination, more than 85 percent were not vaccinated.

Doctors from Germany: “The relationship is still speculative”

Doctors and virologists from Germany consider the conclusions reached by their colleagues from Israel to be premature: “The individual cases described in this study show a certain temporal correlation, which varies so much from case to case that there is a causal relationship my guess Professor Ansgar Lohs, Director of the Clinical Clinic and Polyclinic at the University Hospital Hamburg-Eppendorf, says:

Also interesting: Long-term spread of Covid – what helps fight it in the long run


In general, individual cases are described and treated Insufficient, says Professor Sandra Ciesek, Director of the Institute of Medical Virology at the University Hospital Frankfurt. They are very different. “The heterogeneity of cases is reflected not only in the age of the patients but also in the clinical course. While the two younger children required a liver transplant, the three older children were treated with steroids,” says Cesek.

Older children are too time cycles Very variable. “Whereas the child developed unexplained hepatitis more than four months after infection with SARS-CoV-2, the 13-year-old developed hepatitis at the time of the same infection. Hence, the potential pathogenetic mechanisms in these cases also vary greatly. “.

Virologist Cicek calls for more treatment of hepatitis cases

also extended Viral Test They were inconsistent in cases and in some cases incomplete. “For example, acute hepatitis C infection was not excluded in any of the children,” Cesek continues. Although the study contains some important general considerations about the possible link between hepatitis and Covid-19, it doesn’t help as to why. On the other hand, the proposed association between childhood infection with SARS-CoV-2 and acute liver damage could lead to unfounded concerns.

This is Ciesek Root Cause Analysis incomplete. It is not possible to derive specific recommendations from the five issues. In summary, medically reported cases of severe acute hepatitis in children should be treated carefully. Cysek: “The involvement of SARS-CoV-2 is still neither proven nor excluded.” (Kay)




This article first appeared on morgenpost.de.



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